HPV infection. Approximately 20 million Americans are currently infected with HPV, and another 6.2 million people become newly infected each year. About 75% of sexually active men and women acquire genital HPV infection at some point in their lives.
Genital warts. About 1% of sexually active adults in the U.S. have genital warts at any one time.
Cervical cancer. The American Cancer Society estimates that in 2008, 11,070 women will be diagnosed with cervical cancer in the U.S. 
Other HPV-related cancers are much less common than cervical cancer. The American Cancer Society estimates that in 2008, there will be:

• 3,460 women diagnosed with vulvar cancer
• 2,210 women diagnosed with vaginal and other female genital cancers
• 1,250 men diagnosed with penile and other male genital cancers
• 3,050 women and 2,020 men diagnosed with anal cancer
• Certain populations may be at higher risk for HPV-related cancers, such as gay and bisexual men, and individuals with weak immune systems (including those who have HIV/AIDS) 

RRP is very rare – it’s estimated that less than 2,000 children get RRP every year.